Protein design tools are emerging as a potential solution to the global shortage of snake antivenom, an issue exacerbated by the high demand for effective treatment against venomous bites. Recent developments in biotechnology offer promising avenues for creating synthetic antivenoms through engineered proteins, which could reduce dependency on traditional methods that require the collection of venom from snakes and the production of antivenom in living organisms. This approach not only aims to streamline and accelerate antivenom production but also targets specific venom types more accurately, enhancing treatment efficacy. However, challenges remain, including regulatory hurdles and ensuring that these engineered solutions are safe and effective for human use. The success of these tools could transform emergency medicine and improve public health outcomes in areas prone to snakebites, highlighting a significant opportunity in biotech advancements.