The recent UNSW-led study evaluated the effects of creatine supplementation in 54 individuals participating in a 12-week resistance training program, revealing no significant difference in muscle gains between those taking creatine and those who were not. Comments from users highlight various perspectives, suggesting that while creatine may not directly increase muscle mass, it could allow users to perform more reps, indirectly supporting muscle growth through enhanced performance and recovery. The study also indicated potential issues with sample size and methodology, sparking a debate over the need for larger, more comprehensive analyses. Interestingly, a secondary analysis hinted at a minor benefit for females in terms of lean body mass gains. Overall, the discourse emphasizes the nuanced role of creatine, pointing out that hydration benefits (water retention) and indirect performance enhancements are vital components of its use, especially for those with lower dietary creatine intake, such as vegans.