The post discusses significant issues regarding research integrity in Alzheimer's science, emphasizing the impact of fraudulent studies on both science and individual lives. A personal account illustrates the devastating effects of Alzheimer's disease on families, highlighting the pain caused by misdiagnosis and lack of effective treatments. It points to a systemic problem in biomedical research characterized by data manipulation and pressures within the academic system that prioritize publishing over scientific truth. The ongoing debate over the amyloid hypothesis is addressed, with some experts defending its validity despite fraudulent studies that have criticized it. The need for structural reforms in scientific publishing and research practices is stressed to prevent future setbacks and ensure the credibility of research outcomes.